What is Naltrexone?
In this video, Dr. Ben Nordstrom explains how naltrexone is used to treat opioid and alcohol use disorder and support long-term recovery.
Naltrexone is an FDA-approved medication that works by blocking the effects of opioids in the brain. By doing this, naltrexone helps reduce cravings and lowers the risk of returning to use. It can be an important option for individuals who have already become opioid-free and are focused on maintaining recovery.
How Naltrexone Works
Naltrexone is an opioid antagonist, meaning it blocks the effects of opioids in the brain. This prevents opioids such as heroin, fentanyl, oxycodone, and hydrocodone, from producing effects like euphoria or sedation.
Because it blocks opioid effects rather than activating them, naltrexone does not produce a “high.” It is not habit-forming and does not cause withdrawal when stopped.
When It May Be Used
Care teams typically start naltrexone after a person has been free of opioids for 7-10 days. Starting it too soon can trigger withdrawal symptoms, so proper timing is important.
Providers work closely with each patient to determine when it is safe and appropriate to begin treatment.
Available Options
Naltrexone is available as a daily oral pill (typically prescribed for alcohol use disorder) or a long-acting monthly injection (brand name Vivitrol). These options allow patients and providers to choose an approach that best fits a person’s routine and recovery goals.
The monthly injectable form can be helpful for individuals who prefer not to take medication every day.
Part of a Comprehensive Treatment Plan
Medication is one part of treatment. Naltrexone is often used alongside counseling and other support services to address both the physical and emotional aspects of opioid use disorder.
This combination helps patients stay engaged in care and build skills for long-term stability.
Finding the Right Fit
Every person’s recovery is different. A healthcare provider can help determine whether naltrexone is the right option based on medical history, treatment goals and stage of recovery.
